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In other fictional television works, a January 1971 episode "By the Pricking of My Thumbs ..." of the British science fiction TV series Doomwatch featured an XYY boy expelled from school because his genetic condition led him to be falsely accused of nearly blinding another boy, The false stereotype of XYY boys and men as violent criminals has also been used as a plot device in the horror films Il gatto a nove code in February 1971 (dubbed into English as The Cat o' Nine Tails in May 1971) and Alien 3 in May 1992.

In December 1970, at the annual meeting of the American Association for the Advancement of Science (AAAS), its retiring president, geneticist H.

Developmental delays and behavioral problems are also possible, but these characteristics vary widely among affected boys and men, are not unique to 47, XYY and are managed no differently from in 46, XY males. MI and MII are the stages of meiosis, while the blue and pink circles are male and female cells respectively, and the blue and pink bars are Y- and X-chromosomes respectively.

The purple cell has 2 Y-chromosomes and 1 X-chromosome due to fusing with a male cell with 2 Y-chromosomes, which was due to division problems in MII of the male.

Screening for those X chromosome aneuploidies was possible by noting the presence or absence of "female" sex chromatin bodies (Barr bodies) in the nuclei of interphase cells in buccal smears, a technique developed a decade before the first reported sex chromosome aneuploidy.

An analogous technique to screen for Y-chromosome aneuploidies by noting supernumerary "male" sex chromatin bodies was not developed until 1970, a decade after the first reported sex chromosome aneuploidy.

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In Edinburgh, fifteen 47, XYY boys with siblings identified in a newborn screening program had an average 104.0 verbal IQ and 106.7 performance IQ, while their siblings had an average 112.9 verbal IQ and 114.6 performance IQ.

For the rest of those diagnosed after childbirth, around half are diagnosed during childhood or adolescence due to developmental delays or learning difficulties.

The rest are diagnosed for a variety of reasons including a small percentage due to fertility problems (5%).

In contrast to the other common sex chromosome aneuploidies—47, XXX and 47, XXY (Klinefelter syndrome)—the average IQ scores of 47, XYY boys identified by newborn screening programs were not reduced compared to the general population.

In a summary of six prospective studies of 47, XYY boys identified by newborn screening programmes, twenty-eight 47, XYY boys had an average 100.76 verbal IQ, 108.79 performance IQ, and 105.00 full-scale IQ.

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